About this Event
This event brings together computational researchers from across London's leading institutions, including the Francis Crick Institute, UCL, Imperial, and King's, alongside the AI and biotech community around King's Cross, to spark new collaborations between computational and experimental science.
The programme spans three themes: omics, biomolecular design, and lab in the loop.
The day features invited and contributed talks, plus poster sessions selected from submitted abstracts, with plenty of time for informal discussion over coffee, lunch, and an evening reception. We welcome researchers at all career stages and especially encourage early-career researchers to present their work.
Abstract submission through here.
Confirmed speakers include Michael Sternberg (Imperial), Stefano Angioletti-Uberti (Imperial), Michael Howell (the Crick), Mihaela van der Shaar (the Crick) and a talk on AlphaGenome (Google DeepMind), with more to be announced.
Please don't hesitate to get in touch with any questions at [email protected].
Looking forward to seeing you there,
Computational Biology Symposium organising committee
Marta Sadlej and Alexandru Nicolae-Popescu
Agenda
🕑: 09:00 AM - 09:30 AM
Registration & coffee
🕑: 09:30 AM - 11:15 AM
Session 1 · Biomolecular design
🕑: 11:15 AM - 12:00 PM
Coffee break
🕑: 12:00 PM - 01:30 PM
Session 2 · Omics
🕑: 01:30 PM - 03:00 PM
Lunch & poster session
🕑: 03:00 PM - 04:15 PM
Session 3 · Lab in the loop
🕑: 04:15 PM - 04:45 PM
Closing remarks and prizes
🕑: 04:45 PM - 06:45 PM
Networking, drinks and posters
Session 1
🕑: 09:30 AM - 09:40 AM
Opening remarks
🕑: 09:40 AM - 10:10 AM
09:40–10:10 Stefano Angioletti-Uberti (Imperial College London)
Info: Embed to Align: Using Protein Language Models to enable an interpretable generative approach based on (AI-)directed evolution
🕑: 10:15 AM - 10:45 AM
Michael Sternberg (Imperial College London)
Info: Modelling protein structure, ligands and missense variants in the AlphaFold era
🕑: 10:45 AM - 11:00 AM
Abdolrahman Shams Nateri (University of Nottingham)
Info: From In-Silico SPOCK1-MMP Interaction Dynamics to Patient-Derived Models of Tumour ECM Remodelling
🕑: 11:00 AM - 11:15 AM
Martin Rees (King's College London)
Info: Generation of a de novo designed binder to the massive muscle protein titin for use in fluorescence microscopy
Session 2
🕑: 12:00 PM - 12:15 PM
Theodore de Pomereu (The Francis Crick Institute / Imperial College London)
Info: Let the data write the equations: decoding signalling dynamics with symbolic regression
🕑: 12:15 PM - 12:30 PM
Elizabeth Amelia (Imperial College London)
Info: The Homogenisation Limit: Spatial and Temporal Boundaries of Transcriptomic Biomarkers in Oncology
🕑: 12:30 PM - 12:45 PM
Christian Langridge (UCL / QMUL)
Info: TRACE: a multi-task tabular transformer for differentiation coordinate prediction in human neuroepithelial organoid scRNA-seq
🕑: 12:50 PM - 01:30 PM
Dr Joshua Pan (Google DeepMind)
Info: AlphaGenome Atlas: in silico mutagenesis of the entire human genome improves prioritization and interpretation of non-coding variants
Session 3
🕑: 03:00 PM - 03:30 PM
Mihaela van der Schaar (University of Cambridge / The Francis Crick Institute)
Info: Title to be announced
🕑: 03:30 PM - 04:00 PM
Michael Howell (The Francis Crick Institute)
Info: AI and laboratory automation in discovery research-married bliss or still in the friend zone?
Event venue & nearby stays
The Francis Crick Institute, 1 Midland Road, London, United Kingdom
Concerts, fests, parties, meetups — all the happenings, one place.