23rd International Conference- Tuesday 25th June

The Conference

The 23rd International Conference in Genomics and Proteomics will be held at the University of West London, a new hub for the Microbiomes, Environment and Health group on 24-25 June 2024.

The conference will explore cutting-edge technologies, focusing on in-depth investigations into species variants in outbreak infections to the complexities of diverse ecosystems.

A brief history

Cutting-edge technologies have revolutionised the molecular characterisation of microbial pathogens, moving from single-component identification to comprehensive systems, including microbiomes and ecosystems. Omic technologies have played a crucial role, expanding the scope of Life Sciences over the past two decades. The journey began in 1998 with the live demonstration of the first benchtop MALDI-TOF MS (Kratos Analytical) in the UKHSA's (PHLS, HPA, PHE) lecture theatre. Despite the hiatus of a 3-year COVID-19 pandemic, these conferences continued to this 23rd meeting. The use of MALDI-TOF MS and tandem MS/MS has transformed microbial species identification, reducing identification time from days to minutes. For instance, Salmonella spp. typing shifted from DNA sequence data obtained via MS to current Whole Genome Sequencing in the same laboratory, showcasing the rapid adoption of methods from research to clinical reference laboratories.

The 'One-Health' approach, triggered by the 2003 SARS outbreak, emphasises the accelerated emergence of transmissible diseases in the 21st century, impacting both local human health and global economies. Initially applied in clinical contexts, advanced technologies have expanded to diverse environmental ecosystems, allowing the exploration of resistome structures within the microbiomes of humans, animals, and the environment. To address the field's expanded scope, this conference series has formed alliances with the Animal & Plant Health Agency and other London universities. The current conference continues to explore leading-edge technologies, focusing on in-depth investigations into species variants in outbreak infections to the complexities of diverse ecosystems. It covers areas such as the impact of diverse microbiomes on chronic disease development and the systematic investigation of antibiotic-resistant genes in environmental mapping and tracking.

PROGRAMME : Tuesday 25 June 2024

C) Resistome / MALDI-TOF / Tandem MS

09.00-10.00 Coffee, Exhibition and Posters

09.30-10.00 Antimicrobial Resistance Dissemination and Anti-Plasmid Approaches.

Enas Newire, Department of Natural Sciences, Middlesex University, London

10.00-10.30 Probing the Resistome of Anaerobes Species with MALDI TOF MS

Nurver Ulger Toprak, Marmara University School of Medicine,

Department of Medical Microbiology, Maltepe, 34854-İstanbul

10.30-11.00 The Dawn of Genome-Based Directed Database Strategies for MALDI- TOF MS Bacterial Species and Subspecies Identification

Itaru Dekio1, K. Teramoto2, Y. Fukuyama3, H. Tamura4, The Jikei University School of Medicine, Tokyo1, Shimadzu Corporation, Kyoto2, Koichi Tanaka Mass Spectrometry Research Laboratory, Shimadzu Corporation, Kyoto3, Meijo University, Nagoya, Japan4

11.30-12.00 Electrospray Ionization and Orbitrap MS for Microbiological

Applications

Jenny Ho, ThermoFisher Scientific, Hemel Hampstead, UK

12.00-13.30 LUNCH – EXHIBITION / POSTERS

13.30-14.15 Keynote. Turning Ideas into Impact: The Journey from PhD Research to Established Entrepreneurship. Dr. Emmanuel Raptakis, PhD, MBA Oxford University Innovation, Deputy Head of Licensing and Ventures - Physical Sciences

D) Microbial Typing / Spectroscopy:

14.15-14.45 Liquid Atmospheric Pressure (LAP)-MALDI-MS for the Identification of Bacterial Signatures

Lily Adair, Department of Chemistry, University of Reading, UK

14.45-15.15 MALDI-TOF MS to FT-IR Biotyper; A New Approach to the Typing of Microbial Species

Erika Tranfield, Bruker UK Limited, Coventry, UK

15.15-15.45 FT-IR Biotyper in the Study of Transmission of Veterinary Pathogens

Flavia Zendri and Dorina Timofte. Institute of Infection, Veterinary and Ecological Sciences, Department of University of Liverpool

15.45-16.15 Unravelling the Potential Impact of Ramanomics in Microbial Diagnostics

Jeff Liu, Ramanomics Ltd., PhD in Oncology, University of Oxford

16.15 General Discussion and Closing Remarks

Professor Hermine Mkrtchyan

University of West London

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Event Venue & Nearby Stays

University of West London, Weston Hall, St Mary's Road, London, United Kingdom