Rapid Detection of Resistance to Therapeutic Antibodies

Thu Jun 06 2024 at 12:30 pm to 04:30 pm UTC+01:00

The Wesley | London

Tavistock Run Project
Publisher/HostTavistock Run Project
This is a project 'dissemination event' to describe and NIHR-funded project addressing issues with the use of biologic drugs.
About this Event

This is a project 'dissemination event' to describe an NIHR-funded project addressing issues with the use of biologic drugs.


The basics of the problem surrounding patients building immunity to mono-clonal antibody drugs: These drugs are the current best available treatments for the many auto-immune diseases, but become ineffective after a while as the patient will generate antibodies. Rapid, reliable and simpler detection of these will greatly enhance the clinician's choices in deployment of given treatments, and when to swap to different approaches. By developing new marker assays in tandem with a new camera and sensing method will lead to an in-clinic means of testing for the antibodies, simpler and quicker than sending samples away for analysis in a laboratory.

This will be a general interest event for people affected by diseases and with an interest in developments; clinicians keeping abreast of developments, people interested in the instrumentation challenges.

Draft Agenda

12.30 Registration & Networking, light lunch and refreshments available

13.30 Welcome & Opening Remarks from the Event Chair

Professor Pankaj Vadgama, Emeritus Professor of Clinical Biochemistry, Consultant Chemical

Pathologist

Part 1 — Clinical

13.45 The Importance Of Research : A Patient Perspective

Dominic Shadbolt, Multiple Sclerosis Patient Advocate

14.05 Autoimmune Diseases and how Mono-clonal Antibody drugs work

Sharmilee Gnanapavan, Consultant Neurologist, Barts Health NHS Trust & Princess Alexandra NHS Trust. QMUL: Basics for the people in the room from non-clinical backgrounds

14.30 The Economics of Health

Tim Jamieson, NIHR Fellow in Health Economics at Queen Mary University of London QMUL: How the challenge looks at scale, and the role of Health Economics in general, and in this project.

15.00 Comfort Break

Part 2 — Technical

15.20 Biomarkers: How do they work and what we have looked at

Speaker TBC

15.50 The Camstech SupaCam: building a novel detector system for patient-side chemi/bioluminescence assay

Alex Efimov, Camstech Ltd.


Event Photos
Event Photos

Event Venue

The Wesley, 81-103 Euston Street, London, United Kingdom

Tickets

GBP 0.00

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