Population Genomic Screening - Exploring its Complexities

Thu Oct 23 2025 at 09:50 am to 05:00 pm UTC+01:00

The Royal Society | London

Betty Nixon
Publisher/HostBetty Nixon
Population Genomic Screening - Exploring its Complexities
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Join us to explore the complexities of Population Genomic Screening in person on Thursday, 23 October, 2025
About this Event

Genomic Screening is becoming widely used and in the UK the genomes of all 500k participants in UK Biobank have been sequenced. The UK also recently started two new initiatives; the ‘Generation Study’ to sequence the genomes of 100k babies, and ‘Our Future Health’ that aims to recruit and collect health data and blood samples on up to 5 million adults, with eventual ‘feedback information about disease risks’.

Several questions arise concerning these studies: 1) at a practical level, e.g. the significance of a particular finding in non-symptomatic people with no family history; 2) on an ethical level, e.g. informed consent and long-term data storage; 3) a financial question, e.g. the true cost to health services beyond the screening process; and 4) the impact of a positive screening result on individuals and families.

This conference will explore examples of programmes that have worked, and those that have not worked. To help provide some understanding of the issues involved, talks will cover historical aspects of screening, new initiatives, ethical considerations, impact of findings on health services and families, implementation of new screening methods, and communication.


Agenda

🕑: 10:00 AM - 10:40 AM
Overview of population screening programmes
Host: Professor Richard Houlston
🕑: 11:10 AM - 11:50 AM
A historical perspective on the realities of newborn screening
Host: Professor Diane B Paul
🕑: 11:50 AM - 12:30 PM
Ethical considerations in screening programmes
Host: Professor Felicity Boardman
🕑: 12:30 PM - 01:10 PM
The clinical utility of common genetic variation
Host: Professor David Hunter
🕑: 02:10 PM - 02:50 PM
Polygenic risk scores in population screening and disease prediction
Host: Professor Aroon Hingorani
🕑: 02:50 PM - 03:30 PM
Challenges of communicating the complexities of genomic data
Host: Dr Philip Ball
🕑: 04:00 PM - 05:00 PM
ADELPHI LECTURE: Challenges of population screening
Host: Dr Margaret McCartney
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Event Venue & Nearby Stays

The Royal Society, 6-9 Carlton House Terrace, London, United Kingdom

Tickets

GBP 0.00 to GBP 10.00

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