About this Event
December 2025 - 1043rd Monthly Meeting of NESACS: Med Chem Symposium
"Addressing Pharmacokinetic Challenges in Contemporary Small-Molecule Drug Discovery"
This meeting will be hosted by Pfizer, 1 Portland St in Cambridge, MA
Registration is required and ends at 11:30 PM on November 27, 2025 or when tickets are sold out
Thursday – December 4th, 2025
3:00 pm Welcome
Raj Rajur, Medicinal Chemistry Program Chair
NESACS, MA
3:10 pm Introductory Remarks
Pfizer, Cambridge, MA
3:15 pm – 4:00 pm Maria Madeira
Merck, MA
Title: “TBD”
4:00 pm – 4:30 pm Alec Flyer
Title: Discovery of NVP-MIW491: Dermal Delivery of an LXR Agonist for the Treatment of Meibomian Gland Dysfunction
Novartis, MA
4:30 pm – 5:00 pm Break
5:00 pm – 5:45 pm Randolph Escobar
Title: Design and Synthesis of a Selective HPK1 Inhibitor Phosphate Pro-drug, AZ3201
AstraZeneca, MA
5:45 pm – 6:30 pm Michael Green
Pfizer, Cambridge, MA
Title: Discovery of clinical candidate PF-07293893: A novel and selective AMPK gamma 3 activator for the potential treatment of heart failure
6:30 pm – 8:00 pm Networking Dinner
8:00 pm Closure of Event
THE PUBLIC IS INVITED
ALL ATTENDANEES ARE REQUIRED TO PRE-PAY. WALK-IN’s ARE NOT ALLOWED.
Please use google map: 1 Portland St., Cambridge Massachusetts 02139.
MBTA closest stop is Kendall Sq. or Central Sq. on red line.
Parking: Street parking on Mass Ave., Albany, and Main St.. Parking Garage on the backside of the building has hourly parking at your own expense.
Registration or other questions? Please contact: Raj Rajur [email protected]
Organizing Committee:
Mark Ashwell; Brian. Aquila; Blaise Lippa; Andrew Scholte; David Candito; Michelle Lamb; Silvana Leit; Melissa Grenier-Davies; Paul Scola; Lauren Monovich; Jason Beiger; Paul Greenspan; Raj Rajur
Event Venue & Nearby Stays
Pfizer, 1 Portland Street, Cambridge, United States
USD 10.00 to USD 50.00
