Medicine at the Crick

Thu Jun 06 2024 at 02:00 pm to 05:45 pm UTC+01:00

The Francis Crick Institute | London

The Francis Crick Institute
Publisher/HostThe Francis Crick Institute
Medicine at the Crick
Advertisement
Hybrid event taking place virtually and in person, organised by The Francis Crick Institute, London
About this Event

Inflammation and Cancer Promotion: Revisiting Berenblum


Our event series showcases major advances in biomedical science and raises awareness of the medical implications of major scientific advances. Interested members of the Crick and wider UK biomedical community are invited to attend. Members of the academic medical press are also invited. Each event comprises a series of talks and a panel discussion, followed by networking for in person attendees.

More about the event

This 14th edition of Medicine at the Crick will be hosted by Charlie Swanton (The Francis Crick Institute)

Increasing evidence suggests humans are a patchwork of mutant clones. Indeed, it is estimated that a healthy 60 year old will have over a 100 million mutant clones with oncogenic mutations, yet cancer is not an inevitable consequence of ageing. These data suggest that oncogenic mutations may be necessary for tumour initiation, but they may not be sufficient. In keeping with this, Isaac Berenblum provided evidence that tumour initiation in mouse models was a two-step process. The first, we now know involves the acquisition of an oncogenic mutation, the second, exposure to an inflammatory stimulator such as TPA. The two together are required for tumour formation. Increasing evidence in pancreas, melanoma, glioma, lung cancer and mesothelioma suggest similar initiation/promotion mechanisms are required for tumour initiation. These discoveries have important implications for preventative medicines targeting the first steps in tumour evolution. This Medicine at the Crick event will review the state-of-the-art evidence supporting the Berenblum initiator-promoter model and explore how this knowledge may impact new efforts to prevent tumour initiation and open up a new field of molecular cancer prevention.

Programme

Speakers and panellists include: Dr Direna Alonso-Curbelo (Institute for Research in Biomedicine Barcelona), Dr William Hill (The Francis Crick Institute), Prof Simona Parrinello (UCL Cancer Insitute), Prof Richard Marais (Oncodrug Ltd) and Prof Allan Balmain (UCSF Helen Diller Family Comprehensive Cancer Center)

Lectures will be followed by a Q&A panel discussion and a networking reception for in person attendees until 19:00.

You can find a more detailed programme here.

Registration

We will host this as a hybrid event, with an in-person audience joined by others online. Please book now for a free virtual or in-person ticket. Virtual ticket holders will receive Zoom joining details in advance of the webinar and in-person ticket holders will be emailed with full attendance details closer to the event.

To receive details of future Medicine at the Crick events, email with the subject line 'Subscribe'. In signing up for updates on Medicine at the Crick, you confirm that you have accepted the terms of our . You can unsubscribe at any time by contacting us at the same address

Advertisement

Event Venue & Nearby Stays

The Francis Crick Institute, 1 Midland Road, London, United Kingdom

Tickets

GBP 0.00

Sharing is Caring:

More Events in London

A View From The Bridge
Thu Jun 06 2024 at 01:30 pm A View From The Bridge

Theatre Royal Haymarket

Fawlty Towers - The Play
Thu Jun 06 2024 at 01:30 pm Fawlty Towers - The Play

Apollo Shaftesbury Avenue

The Government Inspector
Thu Jun 06 2024 at 01:30 pm The Government Inspector

Marylebone Theatre

Back To The Future: The Musical
Thu Jun 06 2024 at 01:30 pm Back To The Future: The Musical

Adelphi Theatre

Mrs. Doubtfire
Thu Jun 06 2024 at 01:30 pm Mrs. Doubtfire

Shaftesbury Theatre

Walthamstow  Face:Face Baby Massage for Families in Waltham Forest
Thu Jun 06 2024 at 01:30 pm Walthamstow Face:Face Baby Massage for Families in Waltham Forest

Walthamstow Family Hub

Audio Description for all: focus group 1
Thu Jun 06 2024 at 02:30 pm Audio Description for all: focus group 1

King's College London

London Property Network
Thu Jun 06 2024 at 03:00 pm London Property Network

79 Marylebone High Street,London,W1U 5JZ,GB

Workshop: "Activism in and beyond the University"
Thu Jun 06 2024 at 03:00 pm Workshop: "Activism in and beyond the University"

Queen Mary University of London

Niko Kolodny, UCL Shearman Lectures | 2: A Basis in Sovereignty
Thu Jun 06 2024 at 03:00 pm Niko Kolodny, UCL Shearman Lectures | 2: A Basis in Sovereignty

Central House

Impactful Devolution: Laying the foundations of national renewal
Thu Jun 06 2024 at 03:00 pm Impactful Devolution: Laying the foundations of national renewal

One Great George St

London is Happening!

Never miss your favorite happenings again!

Explore London Events