About this Event
Andy Tay, Presidential Young Professor from National University of Singapore, will be giving a talk in the Department of Materials, G20, on October 21st .
Andy Tay graduated in 2014 from NUS with a First-Class Honours in Biomedical Engineering. He later headed to the University of California, Los Angeles for his PhD studies and graduated in 2017 as the recipient of the Harry M Showman Commencement Award. Andy next received his postdoctoral training at Stanford University before heading to Imperial College London as an 1851 Royal Commission Brunel Research Fellow with Professor Molly Stevens. He is currently a Presidential Young Professor in NUS.
Andy is a recipient of international awards including the Helmsley Fellowship, Toshihiko Tokizane Memorial Award and Endeavour Research Fellowship. He is listed as a 2019 Forbes 30 Under 30 (US/Canada, Science), 2020 World Economic Forum Young Scientist, and 2020 The Straits Times ‘30 and Under’ Young Singaporeans to Watch.
Abstract
Magnetic hydrogels are materials containing magnetic microparticles which help transduce magnetic fields into mechanical forces. In the presence of a static magnet, the stiffness of magnetic hydrogels can be altered to investigate the reversible effects of matrix softening and stiffening on cellular behaviours. In this talk, I will describe how we exploit this feature for cancer study.
Again, when a magnet is moved dynamically relative to cells cultured in magnetic hydrogel, alternating mechanical forces can be applied to cells. Here, I will describe the use of mechanotherapy to polarise tumour-associated macrophages (M2 to M1 bias) to create an immunostimulatory tumour micro-environment that facilitated T-cell mediated cancer killing in vivo.
Event Venue & Nearby Stays
G20, Department of Materials, Imperial College London, Exhibition Road, London, United Kingdom
GBP 0.00