About this Event
The Saint Louis AI Summit is a two-day, city-scale convening that launches the 4th Annual STL TechWeek, positioning St. Louis as a geographic and strategic center of the nation’s AI economy. Located at the crossroads of industry, logistics, research, and talent, St. Louis serves as a natural hub for convening leaders from across the Midwest and beyond to shape the future of artificial intelligence. Hosted at the America’s Center in Downtown St. Louis, the Summit brings together industry, government, academia, startups, and the public sector for one of the largest tech events in Missouri.
DAY ONE - Opening Ceremony
9:30 AM - 4:00 PM (Doors Open at 8:00 AM) in the Ferrara Theatre at the America's Center
April 13 features a full day of high-profile keynotes and mainstage conversations with Fortune 500 CEOs, elected officials, government leaders, and global AI experts. Sessions will focus on the most consequential trends and technology breakthroughs in artificial intelligence—exploring how AI is transforming enterprise, national competitiveness, public policy, defense, manufacturing, healthcare, and the future of work. As a centrally located Midwest convening point, the Summit creates a rare opportunity for cross-sector alignment between coastal innovation centers and the nation’s industrial and agricultural heartland.
DAY TWO - AI TeXpo & Innovation Sessions
9:30 AM - 4:00 PM (Doors Open at 8:00 AM) in Banquet Rooms at the America's Center
April 14 expands into a large-scale TeXpo, hosting 100 tech vendors, as well as, industry speakers across 50 breakout sessions organized into 10 innovation tracks. Attendees will engage in product demos, applied case studies, expert panels, research discussions, and hands-on AI workshops—highlighting how AI is being built, deployed, and scaled across real-world Midwest industries and global markets alike.
Breakout Tracks Include:
- AgriFood AI (Bio-Systems & Consumer Products)
- GeoAI (Spatial Data & Imagery)
- HealthAI (Clinical & Precision Medicine)
- FintechAI (Trust, Risk & Financial Infrastructure)
- Physical AI & Autonomous Industry (Manufacturing & Construction)
- Mission-Critical Intelligence (Defense, Logistics & Supply Chain)
- Future-Ready Workforce (Human–AI Teaming, Education & Workforce Development)
- Digital Transformation (The Generative Enterprise)
- AI-First Ventures (Business & Startup Scaling)
- CyberReadiness (Defensive AI & Security)
The Saint Louis AI Summit is free to attend (registration required) and serves as the capstone opening event of STL TechWeek, reinforcing St. Louis’ role as a Midwest leader in applied innovation, talent development, and AI-driven economic growth. Whether you’re building AI systems, deploying them at scale, shaping policy, or preparing the future-ready workforce, this is where the Midwest’s AI ecosystem comes together—at the center of the country.
Parking is available in the America Center garage, in the nearby Marriott garage, or along the street.
Event Venue & Nearby Stays
America's Center Convention Complex, 701 Convention Plaza, St. Louis, United States
USD 0.00
