Musculoskeletal ageing research from discovery to improved health

12.00-13.00 – Arrival and tea/coffee

13.00-13.15 – Welcome

Session Chair – Malcom Jackson

Co-chair – Chloe Chiou

• 13.15-14.00 – KEYNOTE – Russell Hepple - Up the Junction: Causes and Consequences of Neuromuscular Junction Instability with Aging
  
• 14.00-14.20 – Mathew Piasecki - Losing your nerve: Structure and function of the aged motor unit
  
• 14.20-14.40 – Caroline Staunton - Aquaporins: regulators of H2O2 transport and homeostasis in skeletal muscle
  
• 14.40-15.15 – Coffee/Tea
  
• 15.15-16.00 – Elevated talks
  
• 15.55-16.25 – Anne McArdle - title tbc
  
• 16.25-16.55 – Raymond Reynolds - Assessing vestibular function in age and disease
  
• 16.55-17.10 – Professor Nick Harvey - UKRI MRC National Musculoskeletal Ageing Network
  
• 17.10-17.30 - Anna Durrans and Ross King – Versus Arthritis / MRC perspective
  
• 17.30-18.30 – Drinks reception and poster session
  

09.00-09.15 – Arrival and tea/coffee

Session Chair - John Loughlin

Co-chair – Susanne Wijesinghe

• 09.15-10.00 – KEYNOTE – Professor Ingrid Meulenbelt - Osteoarthritis - from molecular pathways to therapeutic avenues
  
• 10.00-10.30 – Susanne Wijesinghe / Mandy Peffers - The role of extracellular vesicle small non-coding RNAs in synovial fibroblast senescence / How CIMA enabled my progression from ECR to PI
  
• 10.30-11.00 –Simon Jones - Osteoarthritis: synovitis, pain and long non-Coding RNAs
  
• 11.00-11.30 – Coffee/tea
  
• 11.30-11.50 – Sarah Rice - Cartilage epigenetics in joint development and disease
  
• 11.50-12.20 – Mark Wilkinson - What can primary human tissue tell us about bone and cartilage biology?
  
• 12.20-12.50 – Louise Reynard – Using epigenome wide assays and CRISPR editing to identify and validate transcriptional enhancers of OA-associated genes
  
• 12.50-13.50 – Lunch (poster session 2)
  

Session Chair - Beth Phillips

Co-chair - Vanja Pekovic-Vaughan

• 13.50-14.35 - KEYNOTE – Kristen Fortney
  
• 14.35-15.05 – Phil Atherton – Anabolic resistance and ageing
  
• 15.05-15.25 – Dan Wilkinson – The Application of Metabol/Proteomics to Human Skeletal Muscle Ageing Research: Developments to Help Expand Our Insight
  
• 15.25-15.55 – Coffee/tea
  
• 15.55-16.25 – Elevated talks
  
• 16.25-16.55 – Yu Chiang Lai – The molecule mechanism of muscle wasting
  
• 16.55-17.15– Sebastian Serres - Application of dynamic nuclear hyperpolarisation of 13C-labeled pyruvate to investigate muscle pyruvate metabolism during in-bore exercise
  
• 17.15-17.45 – Christine Le Maitre – title tbc
  
• 19.30-21.00 - Dinner
  

09.00-09.15 – Arrival and tea/coffee

Session Chair - Chris Buckley

Co-chair – Blandine Poulet

• 09.15-09.45 – Adam Croft - Fibroblast diversity across the life-course of inflammatory joint disease
  
• 09.45-10.15 – Amy Naylor - Bone damage in inflammation and ageing: Unravelling their relationship at the molecular level
  
• 10.15-10.35 – Elevated talks
  
• 10.35-11.00 – Coffee/tea
  
• 11.00-11.20 – David Wilkinson - Serine proteinases and their inhibitors in cartilage disease and development
  
• 11.20-11.50 - Andrew Filer
  
• 11.50-12.35 – KEYNOTE – Sarah Snelling - Building single cell resolution maps of musculoskeletal tissues
  
• 12.35-13.00 – Prizes and closing remarks
  
• 13.00 – Meeting close
  

Event Venue & Nearby Stays

Edgbaston Park Hotel, 53 Edgbaston Park Road, Birmingham, United Kingdom