About this Event
Gérard Orth was an emeritus research director at the CNRS and honorary professor at the Pasteur Institute and member of the French Academy of Sciences. He was a passionate scientist who dedicated his life to the advancement of our knowledge on the relation between papillomavirus infections and uterine cancer and to the improvement of the prevention of this frequent disease by early screening and vaccination.
Gérard Orth was born in 1936, studied veterinary medicine and started his scientific carrier at the Gustave Roussy cancer Institute in Villejuif (1961-1979). He was invited by François Gros to join the Pasteur Institute where he directed the Papillomavirus unit from 1980 to 2000.
His research was focused on the study of the role of viruses in the cause of cancer in animals and humans. Initially, he studied the Shope Papillomavirus that induces cancerous lesions in the Cottontail rabbits. He demonstrated by in situ hybridization that the viral genome was present in the tumoral lesions. This was followed by the study of the human Papillomavirus.
He discovered the large variety of viral species that infect humans and supported the hypothesis of the viral cause of human cancer, predominantly cervical cancer in females (conference at Cold Spring Harbor, 1977).
He initiated a collaboration with Professor Stefania Jablonska from Warsaw, a dermatologist, to study a rare human disease, Epidermodysplasia verruciform (EV), an autosomal recessive disease associated with a high risk for the onset of in situ carcinoma. He identified the viral species specific for this disease and the two human genes mutated in these families. He showed that these genes products form a complex essential for the cutaneous immune response to viral infections.
In another field, his studies on vaccination against Shope Papillomavirus in rabbits can prevent tumor formation contributed to the later development of vaccination in Young females and males.
REGISTRATION
Limited places - registration required
Conference registration is free and there is no registration deadline. However, Institut Pasteur reserves the right to close online registration without notice once the amphitheater's maximum capacity has been reached.
PRACTICAL INFORMATION
Address : 28 rue du Docteur Roux - 75015 Paris (Welcome from 8:00am)
Metro : Volontaires (line 12) or Pasteur (lines 6 and 12) stations
Bus : 39, 70, 89 lines (stations Volontaires, Vaugirard or Sèvres - Lecourbe stations)
Vélib : 19 Rue Émile Duclaux / 41 Boulevard Pasteur
All persons entering the campus must present their identity card. Bags will be checked by the security guard at reception.
Event Venue & Nearby Stays
Duclaux amphitheater, 28 rue du Docteur Roux, Paris, France
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