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Background: Developing new (triggered) or improving existing inhaler systems for (preterm) neonates and adults requires test benches for the determination of aerosol output and aerosol output rate. Furthermore, real-time measurement of aerosol output and output rate is advantageous with respect to both development costs and development time, especially when using liquid or humidified dry aerosols. The current standard test procedures following ISO 27427, however, are time-consuming. Moreover, these procedures are not applicable to inhalers for preterm neonates, due to their high breathing frequency, low tidal volume, and the dead space in commercially available test benches. We are describing a novel test bench approach combining gravimetric and optical detection to facilitate real-time measurement of aerosol output, aerosol output rate, and aerosol liquid water content in inhalation systems for (preterm) neonates and adults. Methods: We integrated a laser-based optical measurement unit into test benches for π Venue: The Fillmore - Charlotte
π Address: 820 Hamilton Street
πΊοΈ Extended Address: Charlotte, NC 28206
π City: Charlotte
π Location: 35.24, -80.8455Error occurred: DateTime::__construct(): Failed to parse time string (The Fillmore - Charlotte) at position 0 (T): The timezone could not be found in the database
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The Fillmore - Charlotte, 820 Hamilton Street, Charlotte, NC 28206, US, United States
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