Gene Therapy for Epidermolysis Bullosa (EB)

Mon Aug 05 2024 at 01:00 pm

Old Government House, 24 Princes St, Auckland Central, Auckland 1010, New Zealand | Auckland

DEBRA NZ
Publisher/HostDEBRA NZ
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Please join us for a fantastic opportunity to hear Dr Peter Marinkovich, Associate Professor and Director of Bullous Diseases, Stanford University School of Medicine, talking about 'Gene Therapy for Epidermolysis Bullosa', all welcome! Co-hosted by DEBRA NZ and School of Biological Sciences, Auckland University.
Date: Monday 5th August, 1pm
Venue: Old Government House, Auckland University, 24 Princes St, Auckland
The talk will also be available online - email [email protected] for details.
Abstract:
Up until last year, the only tools to treat the group of inherited mechanical bullous diseases epidermolysis bullosa (EB) were supportive measures, but we were helpless to stop blisters, we could only watch them form without being able to do anything. However, research into EB has been recently proceeding at an exponential pace.
Now with the approval of a topical gene therapy that delivers the collagen VII gene directly into patient skin, we finally have a corrective rather than supportive therapy to reverse the fragility and blistering of dystrophic EB. Further refinement and improvements in correcting EB is an incremental process which will be achieved step by step.
Localized corrective gene therapy for dystrophic EB moved us forward, but many more steps are needed for permanent systemic correction of all EB subtypes. However, there is much optimism that we will get there. Work done over many years of EB research has laid the foundation for many discoveries yet to come.
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Old Government House, 24 Princes St, Auckland Central, Auckland 1010, New Zealand, 24 Princes St, Auckland Central, Auckland 1010, New Zealand,Auckland, New Zealand

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